A woman in her 40s is in a critical condition after a three vehicle crash, which closed a major Melbourne freeway.
A 4WD towing a horse float, a car and a truck collided between Montague and Power streets.
The woman had to be cut from the wreckage after the horror crash in Southbank at 12.05pm.
READ MORE: Sydney hotel worker allegedly stabbed in the face with scissors by colleague
A man in his 30s was also rushed to the Albert Hospital in a serious but stable condition.
The truck driver was not injured, and no animals were hurt, police say.
All inbound lanes of the West Gate Freeway have now reopened.
DOWNLOAD THE 9NEWS APP: Stay across all the latest in breaking news, sport, politics and the weather via our news app and get notifications sent straight to your smartphone. Available on the Apple App Store and Google Play.
