Queensland has had some of Australia's strictest border restrictions since the start of the COVID-19 pandemic.
But as of midnight (1am AEDT), the Sunshine State is re-open to domestic travel without any restrictions for all states and territories.
Anyone coming into Queensland, either by road or by air domestically, no longer needs to show a border pass or a rapid antigen test.
READ MORE: Queensland records 23,630 COVID-19 cases and three deaths
However, the government will maintain a mandate requiring people to be fully vaccinated to be able to enter events and venues.
While domestic rules change, international travel restrictions will remain in place until Queensland hits a 90 per cent double-dose vaccination rate.
Currently the state is sitting on 88.5 per cent double jabbed, while 91.5 per cent has had a first dose of the vaccine.
Premier Annastacia Palaszczuk warned Friday the situation could still change in the weeks or months ahead for Queenslanders when she was asked what will happen to the Toowoomba Wellcamp quarantine facility once the state reaches 90 per cent fully vaccinated.
"Don't forget we still have people who fly in who are not vaccinated, we don't know what variant is around the corner," Ms Palaszczuk said.
Queensland Health Minister Yvette D'Ath said the border changes will shift the state's focus "to where people are going" and not where they are coming from.
While Chief Health Officer Dr John Gerrard said the border restrictions had "done their job".
He said their purpose had been to ensure every Queenslander had time to get vaccinated. "It's time for them to come down," he said.
News that Queensland would finally drop its domestic border restrictions after almost two years was made by Ms Palaszczuk on Thursday.
It came much to the delight of residents and their families interstate but also to the Queensland Police Commissioner Katarina Carroll.
Ms Carroll said she was "ecstatic" to have her officers freed up from border control duties, and praised their diligence during the course of the lockout.
Queensland recorded 23,630 new COVID-19 cases and three deaths in the 24 hours to Friday morning.
Earlier in the week, the state recorded its highest daily death tally of pandemic, with six people dying in the 24 hours to Thursday morning.
Source: 9News