Two men killed in four-car and bus crash on Sydney Harbour Bridge

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A second man has died after four cars and a bus crashed at the southern end of the Sydney Harbour Bridge this afternoon.

Three hatchbacks and a luxury car, which appeared to be a Mercedes, collided with the bus, which was not in service, at about 1.40pm.

NSW Police has confirmed two men died at the scene.

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One man has died after three cars and a bus crashed on Sydney's Harbour Bridge.

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Three hatchbacks and potentially a fourth luxury vehicle were involved in the crash. Sydney Harbor Bridge crash

Paramedics have also assessed several other patients.

The bus was driving in the bus lane when the accident occurred. 

The bus driver was not injured.

It is understood the cars were travelling southbound when they collided.

One northbound lane on the Sydney Harbour Bridge has been opened.

The remaining lanes are still closed.

The Sydney Harbour Tunnel remains open in both directions but traffic is heavy. 

A man has died and another is fighting for life after three cars and a bus crashed on Sydney's Harbour Bridge about 1.40pm.

Motorists have been urged to avoid the area.

Buses that normally cross the bridge will start and finish their trips at North Sydney and Macquarie Park.

The train and metro services are still running.

A motorcyclist also allegedly rode through the crime scene while emergency services were dealing with the situation.

He was arrested at the scene and taken to Day Street Police Station. 

More to come.